Preparing and Characterizing Novel Biodegradable Starch/PVA-Based Films with Nano-Sized Zinc-Oxide Particles for Wound-Dressing Applications

Given recent worldwide environmental concerns, biodegradability, antibacterial activity, and healing properties around the wound area are vital features that should be taken into consideration while preparing biomedical materials such as dressings. Some of available dressings present some major disadvantages. For example, low water vapor transmission rate (WVTR), inadequate exudates absorption, complex high cost disposal/recycling processes represent drawbacks. In this paper, starch/polyvinyl alcohol (PVA) material with inserted nano-sized zinc-oxide particles (nZnO) (average size ? 100 nm) was made altered using citric acid (CA). Both ensure an efficient environment for wound-dressing materials. The film were assessed by UV–Vis spectrometry validated against UV light percentage starch/ polyvinyl (PVA)/ nanoparticles composites. Analyses conducted X-ray Spectroscopy (EDX) scanning electron microscopy (SEM) to investigate structure surface morphology Moreover, validate ideal moisture content area, which is necessary optimum wound-healing process, measured. new starch-based exhibited suitable physical chemical properties, including solubility, gel fraction, fluid (scanning imaging), mechanical properties. Additionally, pH level starch-based/nZnO measured study prospect bacterial growth on material. Furthermore, in vitro activity demonstrated effectively inhibited penetration bacteria (Escherichia coli, Staphylococcus aureus).